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In summary, gut microbiota-derived succinate primarily amplifies inflammation and drives the expression of pro-tumorigenic genes through the SUCNR1 and HIF-1 signaling axis, thereby promoting the occurrence and development of CRC in the context of IBD
This ensures proper tracking and prevents any mix-ups
5 Type 2 diabetes and the role of insulin signaling in PD Type 2 diabetes (T2DM) and PD are both age-associated diseases that have a high prevalence due to increased life expectancy
doi:10.1001/jama.2021.2591 Weight Management and Obesity Resource Center
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