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Prior studies have identified the insula as a key region implicated in smoking behavior and nicotine dependence ( However, most previous studies were conducted in general smoking populations without metabolic comorbidities and relied primarily on behavioral outcomes ( In summary, by focusing on patients with T2DM, extending follow-up duration, and integrating functional MRI assessments, this trial aims to address important gaps regarding the potential effects of GLP-1RAs on smoking-related behaviors and their neurobiological mechanisms
These targeted microbubbles specifically bind to vascular endothelial cells expressing VCAM-1 in the early stages of IRI, and changes in their ultrasound signals show good correlation with serum and tissue pathological biomarkers [144]
doi: 10.1097/MCG.0b013e31828f1c6e 563 TegegneBAKebedeB
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