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Grech O, Mollan SP, Wakerley BR, Alimajstorovic Z, Lavery GG, Sinclair AJ
By targeting overlapping yet distinct hormonal pathways, dual incretin therapies aim to amplify weight loss, enhance insulin sensitivity, and improve overall metabolic outcomes beyond what is achievable with GLP-1 receptor agonists alone
C.2001Two distinct 4-hydroxynonenal metabolizing glutathione S-transferase isozymes are differentially expressed in human tissues.282126874 16
In further accordance, the tested agents (i) increase, rather than decrease, and water intake, (ii) block alcohol-induced hyperlocomotion and dopamine release in NAc which are parameters unaffected by aversion, and (iii) attenuates drug-related responses that are driven by reward rather than by malaise [for review see (115)]
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