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While bloating alone rarely necessitates medication discontinuation, persistent severe symptoms warrant thorough evaluation to exclude serious pathology and optimize the treatment regimen
[3] In humans, defects in GSS are inherited in an autosomal recessive way and are the cause of severe metabolic acidosis, 5-oxoprolinuria, increased rate of haemolysis, and defective function of the central nervous system
6, which highlights the potential binding sites for each GLP-1 analog in orange, emphasizing their role in pain modulation
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