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Considerations Do not take Xenical if you: Are pregnant Have malabsorption syndrome Have cholestasis (the slowing or stalling of bile flow through your biliary system) Have a known hypersensitivity to orlistat Additionally, certain medications can interact with Xenical, including: Cyclosporine Levothyroxine Anticoagulants, including Jantoven (warfarin) Amiodarone Antiepileptic medications Antiretrovirals, such as Norvir (ritonavir) Potential side effects include: Fatty stools Gas with oily spotting More frequent or urgent stools Increased defecation Risk of kidney injury Taking a fiber supplement, like psyllium, with Xenical can help reduce GI side effects

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