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In practical terms, a surgical plan may consider: Which area bothers the patient most Which areas can safely be treated together Where scars can be placed as discreetly as possible Whether the patient is still losing weight Medical history, smoking history, medications, and healing risk How much help the patient will have during recovery Whether staging procedures would be safer or more realistic than doing everything at once The Tradeoffs Patients Should Understand Shes also realistic about tradeoffs
2007 Apr;25(2):22331, vii
This has led researchers to explore whether the pair may produce complementary or synergistic signaling responses in selected in-vitro and in-vivo systems
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