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Kremser, K., Kremser-Jezik, M

Song et al showed that decreasing periplasmic GSH by deleting the GSH exporter CydD triggers the CpxR/SoxS two-component systems, upregulating the AcrAB-TolC pump and lowering intracellular drug accumulation

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RESEARCH HIGHLIGHT In the phase 3 EVOKE(+) trials, semaglutide did not slow clinical progression of Alzheimers disease, but the findings provide new insights in the ongoing quest for treatments