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The most promising compounds, 39 and 40 (Figure 6), showed an IC 50 of 2.80 nM against DPP-4 catalytic activity, with 20 - 40-fold selectivity over the DPP-8 and DPP-9 isozymes

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PubMed Lau, D.C.W., Erichsen, L., Francisco, A.M., Satylganova, A., le Roux, C.W., McGowan, B., et al

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