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The hearts were removed on day 2 after IRI for TTC staining to measure infarct size
In order to combat this, natural substances like dasatinib, quercetin, and fisetin that inhibit the PI3KAKT pathway and senolytic agents like Navitoclax (ABT-263), which targets BCL-2 family proteins, are being investigated to reduce therapy-related side effects and specifically eradicate senescent tumour cells (Zhu et al
Nutrients and phytochemicals: from bioavailability to bioefficacy beyond antioxidants
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