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In addition, excessive APAP upregulates TNF-, TGF-, IL-6 and platelet-derived growth factor (PDGF) -B levels in liver tissues of ecto-nucleotide triphosphate diphosphohydrolase-2 (NTPDase2) deficient mice, thereby aggravating AILI and increasing hepatic necrosis [232]

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10.1155/2012/734125 75 MorrisG.AndersonG.DeanO.BerkM.GaleckiP.Martin-SuberoM.et al (2014)