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HIRAOKA, A., KIGUCHI, D., NINOMIYA, T., HIROOKA, M., ABE, M., MATSUURA, B., HIASA, Y
How do I know if I need a B12 supplement
Research shows that in senescent cells, p53 levels are maintained low through ubiquitination while its pro-apoptotic activity is repressed through nuclear segregation by FOXO4. The peptide's competitive inhibition restores p53 activity by promoting nuclear exclusion, allowing p53 to execute its pro-apoptotic program and eliminate senescent cells through targeted pathway activation
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