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The intake level of dietary Met could affect the lipid and bile acid metabolism in the liver in mice, and Met-restricted diet could restore the normal bile acid pool in the liver (82)
Conclusion Just like the weather forecast, your skin can be unpredictable during the monsoon
A larger phase 2b trial by Metabolic Pharmaceuticals (the original sponsor) in 2007 with 534 obese patients failed to show statistical superiority over placebo at 24 weeks
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