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Left untreated, DKA can lead to severe dehydration, cerebral edema, and coma
Mechanistically, the degradation of ARNTL/BMAL1 leads to the upregulation of EGLN2 (hypoxia-inducible factor 2) and subsequently suppressing the function of HIF1A (hypoxia-inducible factor 1 subunit alpha)
[10] Relative contraindications encompass early polycythemia vera, tobacco amblyopia, and concurrent sensitivity to benzyl alcohol used as a preservative
During organogenesis, lower doses approximately 0.1 to 1 times the clinical dose caused delayed skull ossification in rats
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