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In Genfits large international Phase 2b trial, Elafibranor delivered NASH resolution without worsening of fibrosis and improved the metabolism of triglycerides and lipids in patients with advanced disease

The clinically-used artemisinins, such as artemether, artesunate and dihydroartemisinin (DHA), are semisynthetic derivatives of the natural product artemisinin and possess a 1,2,4-trioxane core incorporating a peroxide bond that is essential for activity 2

That said, theres a lot of attention on GLP-1 agonists for weight loss and diabetes, which means theres going to be a lot of funding for research

Specifically, the O3 regime was more effective, achieving a 99% reduction in AFB1 and AFG1, a 60% reduction in AFB2 and AFG2, and a 70% reduction in OTA after 60 min at a 4 cm distance from the plasma source