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In a total of 20 studies (14 observational studies, 1 intervention study, and 5 rodent studies) for the systematic evaluation and analysis of VD and PD, it was reported in a meta-analysis of six observational studies reporting differences in VD levels that mean serum 25(OH)D levels in PD patients were lower than those in healthy controls, five studies in animal models of PD showed that supplemental VD intake in rodents significantly increased the concentrations of tyrosine hydroxylase, promoted the conversion of dopamine neurotransmitter, significantly decreased oxidative damage to the substantia nigra, and significantly increased dopamine levels and neuronal survival in the substantia nigra (87)
FDG PET/CT can help in distinguishing between benign and malignant lesions and in assessing treatment response in MMNSTs (36)
The studies vary significantly in sample sizes, recruitment strategies, and microbiota characterization methods, with most using culturing or 16S amplicon sequencing and only one employing whole genome shotgun sequencing
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